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- $Unique_ID{BRK03042}
- $Pretitle{}
- $Title{azathioprine}
- $Subject{Imuran Burroughs Wellcome Immunosuppressant azathioprine rejection
- kidney transplants severe rheumatoid arthritis}
- $Volume{}
- $Log{}
-
- Copyright (C) 1993 Publications International, Ltd.
-
-
- azathioprine
- ------------------------------------------------------------------------------
-
- BRAND NAME (Manufacturer)
-
- Imuran (Burroughs Wellcome)
-
- TYPE OF DRUG
-
- Immunosuppressant
-
- INGREDIENT
-
- azathioprine
-
- DOSAGE FORM
-
- Tablets (50 mg)
-
- STORAGE
-
- Azathioprine should be stored at room temperature in a tightly closed,
- light-resistant container.
-
- USES
-
- This medication is used to prevent rejection of kidney transplants and to
- control the symptoms of severe rheumatoid arthritis. It is not clear exactly
- how azathioprine works, but it is known to act on the body's immune system.
-
- TREATMENT
-
- In order to prevent nausea and vomiting, you can take azathioprine with
- food or after a meal (unless your doctor directs you to do otherwise).
- Try not to miss any doses of this medication. If you do miss a dose,
- take the missed dose as soon as possible, unless it is almost time for the
- next scheduled dose. In that case, do not take the missed dose at all; just
- return to your regular dosing schedule. Do not double the next dose. If you
- miss more than one dose, CHECK WITH YOUR DOCTOR.
-
- SIDE EFFECTS
-
- Minor.
-
- Diarrhea, nausea, or vomiting. These side effects should disappear over
- time and as your body adjusts to the medication.
-
- Major.
-
- Tell your doctor about any side effects that are persistent or
- particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
- darkened urine, fever, hair loss, joint pains, mouth sores, muscle aches, skin
- rash, sore throat, unusual bleeding or bruising, or yellowing of the eyes or
- skin.
-
- INTERACTIONS
-
- BE SURE TO TELL YOUR DOCTOR if you are already taking allopurinol. This
- medication can possibly increase the blood levels of azathioprine, which can
- lead to serious side effects.
-
- WARNINGS
-
- * Be sure to tell your doctor about any unusual or allergic reactions
- that you have had to any medications, especially to those you may have
- experienced after taking azathioprine.
- * Before starting to take this medication, be sure to tell your doctor if
- you now have or if you have ever had gout, kidney disease, liver disease,
- pancreatitis, or recurrent infections.
- * Azathioprine is potent medicine. Your doctor will want to monitor your
- therapy carefully with blood tests, so that you take the least amount of the
- drug possible.
- * Do not stop taking this medication unless you first check with your
- doctor. Stopping therapy with this drug abruptly may lead to a worsening of
- your condition. Your doctor may, therefore, want to start you on another drug
- before therapy with azathioprine is stopped.
- * There is a chance that azathioprine may cause unwanted effects months
- or years later. These delayed effects may include certain types of cancer.
- Be sure to discuss these possible effects with your doctor.
- * Azathioprine can increase your susceptibility to infections. It is,
- therefore, important to contact your doctor at the first sign of infection.
- Your dose of azathioprine may need to be adjusted.
- * Be sure to tell your doctor if you are pregnant. Birth defects have
- been reported in the offspring of animals that received large doses of
- azathioprine during pregnancy. This drug also has the potential for producing
- birth defects in human offspring. Use of this drug is not recommended during
- pregnancy. There is a possibility that birth defects may occur in the
- offspring if either the male or female is using this drug at the time of
- conception. Use of birth control is recommended while taking this drug.
- Also, tell your doctor if you are breast-feeding an infant. It is not known
- whether azathioprine passes into breast milk.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-